Efficacy and safety of the newer oral hypoglycemic agents in patients with T2DM during Ramadan: A systematic review and meta-analysis

نویسندگان

چکیده

AimsThis systematic review and meta-analysis aims to evaluate the safety efficacy of newer glucose lowering treatments on glycemic control, weight, blood pressure hypoglycemia in patients with T2DM during Ramadan.MethodsA literature search was done PubMed, Embase, Cochrane Library. Quality assessment using ROBINS-I tools for risk bias analyses were performed RevMan version 5.3.ResultsA total 20 studies included meta-analysis. Dipeptidyl peptidase-4 inhibitors (DPP-4i) led a significant reduction HbA1c (%) (SMD -0.25) non-significant decrease weight (kg) -1.06) Ramadan. Glucagon-like peptide (GLP-1) agonist therapy associated -0.68) -2.57) systolic (SBP) (mmHg) -3.50) after Sodium-glucose co-transporter 2 inhibitor (SGLT-2i) -0.51) -1.41), SBP -1.10) diastolic (DBP) -2.08) Ramadan.ConclusionsThis shows clinical benefits medications who fast

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ژورنال

عنوان ژورنال: Diabetes Research and Clinical Practice

سال: 2021

ISSN: ['1872-8227', '0168-8227']

DOI: https://doi.org/10.1016/j.diabres.2020.108562